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Subsequent clinical studies with liraglutide and semaglutide confirmed these findings, and further demonstrated the effect to be mediated via reduced energy intake

In another study, when mouse Hepa1c1c7 cells were incubated with 25 m SFN, an increase in NAD(P)H:quinone oxidoreductase 1 activity was observed, reaching a maximum induction of three-fold over control ( Reference Matusheski and Jeffery 21 )

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