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This section discusses general scientific concepts and does not constitute an endorsement of any specific product or clinical claim

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23, 24, 25 In the adult kidney, AT 2 receptors are mainly localized in the glomerular mesangial cells 22, 26, 27 or the adventitia of the preglomerular arcuate and interlobular arteries

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Key Differences: Metformin stands out as the preferred first-line therapy for most newly diagnosed patients, largely due to its extensive research background and lower cost, as generic versions are readily available [17]

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doi: 10.1172/JCI44774 150

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