Funding The National Key Research and Development Program of China (2020YFA0908200 and 2020YFA0710800), the Key Program of the National Natural Science Foundation of China (81930043 and 82330055), the National Natural Science Foundation of China (T2225003, 82001719, 52073060, and 61927805), the Natural Science Foundation of Jiangsu (BE2018707), the Nanjing Medical Science and Technique Development Foundation (ZKX21019) and the Clinical Trials from Nanjing Drum Tower Hospital (2022-LCYI-ZD-01)
Early studies indicated potential risks for conditions like gallstones, pancreatitis, kidney dysfunction, and even vision changes
Folic Acid acts as a coenzyme in nucleic acid synthesis and amino acid metabolism, essential for the production and maturation of red blood cells and healthy fetal development
Focus on whole foods rich in protein, healthy fats, and complex carbohydrates to sustain energy throughout the day
While the list of pathophysiologic defects continues to grow, the ominous octet provides a representation of 8 key defects found in T2DM ( Figure 1 )