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G Consortium (2003) The international psoriasis genetics study: assessing linkage to 14 candidate susceptibility loci in a cohort of 942 affected sib pairs

Goal: Maintain testicular volume and function during TRT Approach: HCG 500 IU subcutaneously every other day (3x weekly) Begin same time as testosterone therapy Continue for duration of TRT Monitoring: Baseline testosterone, estradiol, LH, FSH Recheck at 6 weeks, then quarterly Adjust based on estrogen response Expected results: Maintained testicular size Preserved fertility potential Possible slight testosterone boost above TRT alone Protocol for fertility restoration on TRT Men on TRT who want to conceive face a decision

GLP-1 and GLP-1+GIP medications have substantial clinical evidence demonstrating weight reduction in studied populations when combined with lifestyle modifications

Its typically defined by therapy gaps of 60 days or more, or when the Proportion of Days Covered (PDC) falls below 80%

In 2017, the State of California settled with the Ozempic manufacturer for promoting a type 2 diabetes drug outside of what it was approved to be used for