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In addition, suppressed miRNA expression of CYP2E1, GSTpi, and TNF- along with enhanced mitochondrial bioenergetics were suggested to be responsible for the protective effect

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The post says that for constipation persisting beyond three to four weeks, providers may prescribe agents that enhance intestinal secretion, naming linaclotide and lubiprostone as examples that counteract the motility-slowing effect

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