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In the above animal model, cotadutide administration was associated with reduction of hepatic inflammation and fibrosis, as indicated by decreases in quantitative measures of liver fibrosis, circulating collagen markers, and inflammatory/pro-fibrotic genes [39]

Participants in Phase 2 trials showed significant reductions in fasting glucose, HbA1c, triglycerides, blood pressure, and waist circumference

They are intended to be used in food, beverage, cosmetic, pharmaceutical applications or/and to help maintain & support a healthy lifestyle

One study [64] found that ACC glutamate levels were decreased in individuals who used cannabis regularly, while these results were not replicated in another study [65]

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