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Second, it is able to induce the combination of ,-unsaturated ketones and GSH through the nucleophilic addition reaction, depleting GSH and reducing the amount of GSH available to combine with chemotherapeutic agents, thus producing an overall GST-inhibitory effect by sensitizing a cell to chemotherapeutic agents

The CD36 or fatty acid translocase protein is a membrane glycoprotein involved in the uptake of those long-chain fatty acids [5], and its ambivalent role in cancer progression and metastasis according to the metabolic context has been well documented [6, 7]

Tirzepatide reduces 24-Hour ambulatory blood pressure in adults with body mass index 27 kg/m 2 : SURMOUNT-1 ambulatory blood pressure monitoring substudy

[DOI] [PubMed] [Google Scholar] 57.Chen J.-R., Hsu S.-F., Hsu C.-D., Hwang L.-H., Yang S.-C

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