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Crucially, pharma companies are not and will not pursue indications for GLP-1 drugs for addiction because they avoid studying unstable populations due to reputational risk and market-size uncertainty
Based on these pathways, GLP-1RAs improve metabolic disorders to alleviate cardiomyocyte dysfunction
1921 This has been attributed primarily to increased gastrointestinal oxalate absorption, leading to greater urinary oxalate excretion, 1921 but also to lower citrate excretion and lower urine pH
The research from the FDA Adverse Event Reporting System revealed elevated reporting odds ratios for alopecia with semaglutide (2.46) and tirzepatide (1.73), though notably not with older GLP-1 medications like liraglutide or dulaglutide
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