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While peptide therapy may possess significant therapeutic and regenerative potential, it is critical that orthopedic and sports medicine providers understand the current lack of evidence to support the clinical use of these peptides, the authors concluded

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The peptide adopts a structural configuration in which the histidine imidazole nitrogen, the glycine amino terminus, and the deprotonated amide nitrogen of the glycine-histidine peptide bond all participate in coordinating a divalent copper ion

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