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Trulicity (dulaglutide) weekly injection dosing schedule Trulicity is started at 0.75 mg per week and titrated as follows: Weeks 1-4 (starting dose): 0.75 mg once a week Weeks 5-8 : 1.5 mg once weekly Weeks 9-12 : 3 mg once weekly if the lower dose is ineffective

This extends the total time to reach the maintenance dose but substantially reduces the likelihood of side effects that cause discontinuation

Acknowledgements We thank the Fondazione Romeo e Enrica Invernizzi for extraordinary support

"Glucagon-Like Peptide-1 Analog, Liraglutide, Delays Onset of Experimental Autoimmune Encephalitis in Lewis Rats"

Dietary composition is perhaps the most important determinant of GLP-1 secretion