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Taxanes have also been reported in preclinical models of prostate cancer to inhibit nuclear translocation of the androgen receptor (AR), thereby decreasing the pro-tumorigenic transcriptional activity of AR 14,15

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In the shRNA PTSD group, astrocyte-specific fluorescence intensities were measured in areas containing both DAPI and mCherry signals indicating Lenti-pSico-MAOB-shRNA-GFP (Sc shRNA) and AAV-GFAP104-Cre-mCherry expression

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Cheah S, English DR, Harrison SJ, Vajdic CM, Giles GG, Milne RL