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Studies have reported OCTN2 expression in respiratory epithelial cells and alveolar macrophages, which is especially high in the upper lung region [301], and OCTN2-mediated carnitine uptake plays an important role in maintaining respiratory cilia beating and airway mucociliary clearance function, helping to remove excess mucus and potentially harmful substances from the airway [302]

doi: 10.14336/AD.2024.0407, 94

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Emerging Therapies: A Shift Toward Targeted Therapy Several targeted therapies approved for AD have also been increasingly investigated for their potential use in CHE