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Driven by the hypothesis that Long COVID is fundamentally rooted in neuroinflammation and mitochondrial dysfunction, clinical trials have begun testing metabolic interventions

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Statements Author contributions PT, JX, and SQ generated the presented idea in this manuscript

However, fasted rats recorded a decrease in the number of hypothalamic cells expressing mTOR and S6K1 activated forms specifically in the arcuate nucleus, with these changes responding to the availability of nutrients [119]

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