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It suppresses the release of glucagon, another hormone that raises blood sugar

Reduction in calorie intake is dose-dependant and does not differ between obese and lean subjects.35 The feeling of satiety produced by OXM and GLP-1 is likely due to their effects on the CNS as well as on gastric emptying

These include the 2-oxoglutarate dehydrogenase (-ketoglutarate dehydrogenase) complex (OGDC), and fumarate hydratase (fumarase)