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Amycretin is years from potential approval
As discussed above (in the section Role of mitochondria in synaptic transmission), Ca 2+ signaling is involved in the accumulation of mitochondria at the postsynaptic regions, where these organelles participate in neuronal Ca 2+ buffering and support of neurotransmission [93]
The relative contribution of each factor cant be separated
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The authors describe the high clinical benefit rate in their cohort as a clarion call for rigorous, systematic investigation, but thus far there has been no large-scale or prospective, controlled investigation for MCAS
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