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Unlike traditional anti-angiogenic therapies that target VEGF, Sylentis developed SYL1801, an siRNA targeting NOTCH Regulated Ankyrin Repeat Protein (NRARP), to prevent and control nAMD progression

doi: 10.1016/j.plefa.2008.07.005

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8.2 The Saturation Hypothesis From SURPASS-CVOT SURPASS-CVOT compared tirzepatide directly with dulaglutide and met its prespecified noninferiority margin but not formal superiority (HR 0.92, 95.3% CI 0.831.01