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Key Points Semaglutide causes diarrhea through multiple mechanisms slowing stomach emptying while speeding up colon activity and affecting nutrient absorption Higher semaglutide doses used for weight loss (Wegovy) cause more GI issues than diabetes doses (Ozempic) Most people see improvement over time as their body adapts to the medication The diarrhea doesn't mean the drug is "working better" Starting semaglutide (Ozempic or Wegovy) can be an exciting development in your diabetes or weight loss journey

1A) to determine possible variations in the metabolite profile between the two groups

Your semaglutide treatment provider will evaluate your medical history, medications, lifestyle, and goals to create a specialized plan for you

Li et al., 2009)

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