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Microscopy The tissue specimens were immediately fixed in buffered formalin (pH 7.4), for 24 hours, dehydrated, and embedded in paraffin wax

Common triggers of mast cell activation include: Food allergens (dairy, gluten, alcohol, fermented foods) Environmental toxins (heavy metals, chemicals and VOCs) Stress and trauma Chronic infections (Lyme, Epstein-Barr, Candida, SIBO) Mold and mycotoxin exposure When mast cells are constantly activated, histamine release becomes excessive, leading to chronic inflammation, tissue damage, and widespread symptoms that seem to come from nowhere

Nutrients could modulate apoptosis for example by inhibiting pro-apoptotic BAX and (pro-)caspases and stimulating anti-apoptotic Bcl-2 [75, 81, 117, 145]

Physicians from this tradition may employ traditional pharmaceuticals, BPC-157 peptides, and complementary therapies