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As an antioxidant, glutathione enables precise direct or indirect control of ROS (such as singlet oxygen, superoxide anions, hydrogen peroxide, etc.), which often accumulate/produce at high levels during biotic stress, thereby reducing damage to the cells (Zechmann, 2020)

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The presence of chronic hyperglycemia, insulin resistance, oxidative stress, and pro-inflammatory mechanisms contribute to endothelial dysfunction in patients with diabetes mellitus (61)

It inhibits tyrosine activity which reduces the production of eumelanin and promotes the pheomelanin production

Overall incidence of cardiovascular events was 24.77, inclusive of coronary artery disease/congestive heart failure (40.1), myocardial infarction (7.1), and stroke (8.1)