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Myra Ahmad, told EMARKETER that drug personalization is needed for patients who may require a lower dose or a different formulation due to experiencing side effects

MAPK phosphatases can dephosphorylate and inactivate kinases in the cascade, but ASK1/2 keeps getting reactivated from the continued oxidant stress, leading to activation of JNK

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Microglia reside in the CNS and play a major role in the innate immune response and secrete various cytokines like interferons (IFN ), Interleukin 1 (IL-1), Tumor Necrosis Factor (TNF)- and chemokines besides MHC Class II molecules