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While the treatment with Ru(II)-OH or NP2 slightly elevated the ROS levels inside the hypoxic cancer cells, the treatment with NP4 showed a strong enhancement of ROS

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The protolerogenic effect of A1AT is evident on dendritic cells (DCs): these cells, at the interface between innate and adaptive immunity, are responsible for antigen presentation to T lymphocytes and priming of naive T cells

Answer : Possibly, but side effects tend to be mild and tend to resolve without intervention once the body gets used to the supplement

In addition, AML cells overexpressing WT BCAT 1 had lower ROS, and the number of bone marrow markers (CD11b, CD14, CD68, and CD36) that marked cell differentiation on the cell surface was lower, suggesting the involvement of the BCAT 1 CXXC motif in ROS buffering and cell development in AML cells