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P38MAPK inhibition The p38MAPK inhibitor SB203580, by decreasing the transcriptional activity of NF-B, has been shown to reduce the levels of mRNA of genes of SASP factors in human senescent cells (81)

Trichoscopy A non-invasive diagnostic technique using a specialised microscope (dermoscope) to examine the scalp and hair follicles at high magnification

Discovered in 1973 by Loren Pickart and shown in Nature to prolong liver cell survival 17 , it has since accumulated more than 50 years of peer-reviewed research on collagen and elastin synthesis, fibroblast activation, gene-expression modulation, and wound healing

The peptide also promotes polarization of macrophages from pro-inflammatory M1 phenotypes toward tissue-repairing M2 phenotypes, with treated macrophages showing 70% increased phagocytic activity for clearing inflammatory debris and 3-fold higher production of VEGF compared to untreated controls

The PRP is then injected across the thinning areas in a series of tiny injections