After completing a full rotation within the abdomen over 4 weeks, switch to the upper thigh for the following month, then the upper arm
Similar to the DCCT/EDIC, after 10 years of observational follow-up, those originally randomized to intensive glycemic control had significant long-term reductions in MI (15% with sulfonylurea or insulin as initial pharmacotherapy, 33% with metformin as initial pharmacotherapy) and all-cause mortality (13% and 27%, respectively) ACCORD, ADVANCE, and VADT suggested no significant reduction in CVD outcomes with intensive glycemic control in participants followed for shorter durations (3.55.6 years) and who had more advanced type 2 diabetes than UKPDS participants
This is exactly the kind of interlocking problem that GLP-1 medications are well-positioned to address, at least partially
Intensive stress/recovery protocol For periods of high stress, poor sleep, or recovery from illness/injury
Oral beta-alanine ingestion increases muscle carnosine content although large variation in response to supplementation exists and the amount of ingested beta-alanine converted into muscle carnosine appears to be low