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ROS generation rises in parallel with fat adipocyte fat accumulation, and the increase in the level of FFAs also stimulates adipocyte ROS generation via NADPH oxidase activation and decline in enzymatic antioxidant expression [115]

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Mild side effects reported in some studies include nausea, headache, or digestive discomfort, typically when starting at high doses

doi: 10.1111/j.1365-2958.2006.05302.x 53 Ansari MR-NMDolatkhahHFattahiEAghazadeAMMojtabaii-MotlagS

The most popular biocompatible polymer used to modify the GO surface is PEG, as it can be easily connected with various anticancer drugs and has continuous release behaviors