GLP-1Rs are widely expressed in the whole body including the kidney [1, 10,11,12,13,14,15] and GLP-1 has diuretic and natriuretic effects in humans and animal models of hypertension, diabetes and obesity [10, 12, 13, 16]
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The maximum dose is introduced gradually, ensuring steady improvements without overwhelming the patient
Talking with a clinician who knows your full medical history is the best way to learn whether a GLP-1 might benefit you

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