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Nyberg, K

[DOI] [PMC free article] [PubMed] [Google Scholar] 172.Lo R.Y., Figueroa K.P., Pulst S.M., Lin C.Y., Perlman S., Wilmot G., Gomez C., Schmahmann J., Paulson H., Shakkottai V.G., et al

However, the lack of a major effect on Ex4 affinity suggests that, either it does not interact with Thr 149 , or else it interacts with a region not essential for affinity, such as the N-terminus

Additionally, injections avoid issues such as nasal irritation or variable absorption tied to conditions like allergic rhinitis or congestion, factors that can affect nasal delivery

In: In vitro and in vivo, in oxidative folding of proteins: basic principles, cellular regulation and engineering