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Transcriptome analysis of pathway enrichment (Supplemental Figure 6A) and gene set enrichment analysis (GSEA) Supplemental Figure 6B) indicated that the hallmark pathway of glutamine family amino acid metabolic process was among the top-ranking upregulated gene sets in A2ARi-treated cells

ZG: Writing original draft, Supervision, Writing review & editing, Project administration, Methodology, Conceptualization, Validation

Both types of media were enriched with 10% fetal bovine serum and 0.1% penicillin and streptomycin

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The formula adds holistic metabolic support through adaptogens like Maca Root and Eleuthero (Siberian Ginseng) to help the body manage cortisol and stress-driven fat storage, thermogenic compounds like Guarana Seed for natural metabolic rate enhancement, and appetite-regulating ingredients like African Mango Seed and Gymnema for blood sugar stability