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The timing-specific modulation suggests BPC-157 specifically interferes with ketamine-induced molecular cascades

DFP, as a more conservative iron chelator with milder iron binding affinity than DFO (Cabantchik et al., 2013), is smaller and considerably more lipophilic than DFO, which allows it to cross cell membranes and penetrate into subcellular organelles, making it one of a few iron chelators that can effectively cross the BBB and access CNS iron pools (Boyuklieva et al., 2024

246 Therefore, obesity seems to be a double-edged sword for cancer immunotherapy, and the underlying mechanisms remain unclear and require further investigation

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