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They'll also typically want evidence of prior attempts at lifestyle-based weight management and confirmation that a licensed provider has evaluated you

Key considerations Unlike the standard approach, which assumes that more medication is better, microdosing challenges the one-size-fits-all mindset

Maybe not so much anymore

In the STEP 1 trial, Semaglutide 2.4 mg weekly produced an average weight loss of 14.9% at 68 weeks, versus 2.4% with placebo (Wilding et al., NEJM 2021