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Where a typical meal may wear off within two hours, people on cagrilintide often report satiety lasting four to six hours

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Of note also Aspartame, Acesulfame K, Glycyrrhizin and Saccharin bind the sweet receptor heterodimer Tas1R2/3 and they have shown to stimulate GLP-1 secretion in the human duodenal adenocarcinoma-derived HuTu-80 cell line (245, 246)