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Rinsing with water or a sodium bicarbonate solution after any reflux episode helps neutralize acid when saliva cannot do the job effectively

Status: Early-phase human trials Not commercially available SC injection (research settings) Caveat: Strong mechanistic case

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Overexpression of DKK1 in conditions like HNSCC and HCC correlates with increased tumor growth and elevated PD-L1 expression, indicative of a cold tumor phenotype characterized by MDSC abundance and diminished CD8 + T cell infiltration [166]