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As we get older, the production of both slows down

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The obesity trial showed weight reductions of up to 14.7% at 36 weeks with the 45 mg dose, while the diabetes trial demonstrated HbA1c reductions of up to 2.1 percentage points and weight loss of up to 10.1 kg at 26 weeks

Little successes, such as slipping back into old jeans or being able to keep pace with your friends, can trump kilos shed