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Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

"We have long been believers that clinicians should turn to a variety of drugs, devices, and procedures in the treatment of diseases." In April, top-line data from Eli Lillys phase III SURMOUNT-OSA trial comparing the efficacy of GLP-1s alone and in combination with positive airway pressure (PAP) in OSA patients over 12 months

GH pulses are exquisitely sensitive to insulin: a carbohydrate or high-fat meal drives insulin up, and elevated insulin suppresses GH release almost immediately, so a dose taken on top of a recent meal is partly wasted

Chronic Fatigue Syndrome can feel isolating, but recovery is possible when you treat the root causes, not just the symptoms

Nat Rev Mol Cell Biol (2006) 7(7):47383