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Furthermore, glutamine can change the composition or function of microbiota [78] by potentially influencing gut microbial metabolism, including the production of the metabolites from the tumor-promoting/suppressing gut microbiome, metabolites that contribute to extracellular acidosis, and short-chain fatty acids (SCFAs) that provide energy to colonic epithelial cells [85,86,87,88]

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This reserve is most impressive at the time of diagnosis, when 50% of the capacity is still present

For example, some rodents, such as mice ( Mus musculus ) and rats ( Rattus norvegicus ), have two copies of the insulin ( Ins ) gene, while other mammals only have single copy of this gene (45, 82)