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Mineralocorticoids, whether in excess (Hyperaldosteronism) or in deficiency (Hypoaldosteronism), are linked to oxidative stress, mainly via activation of the renin-angiotensin-aldosterone system (RAAS) and disruption of cellular homeostasis due to sodium and potassium imbalances

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Total RNA was extracted from flash-frozen LV tissue using the TRIzol RNA extraction method

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doi: 10.1155/2016/4394261