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Die hormonelle Achse wird teils direkt (Glucagon), teils indirekt (CRH Cortisol), teils durch den Sympathikus aktiviert (Adrenalin)

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Incretins are hormones released by your small intestine and are sent out to your body after you have eaten a meal

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In models of obesity or cardiac stress, activation of the GLP-1 receptor has been shown to reduce ventricular hypertrophy and interstitial fibrosis, preserve mitochondrial structure and function, and reduce oxidative stress via the Nrf2/HO-1 signaling pathway 64,65