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In India, community-based studies conducted over the past decade on apparently healthy individuals have reported Vitamin D deficiency prevalence rates ranging from 50% to 94%

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The incorporation of medicinal plants in the formulation and administration of ocular remedies stands as a cornerstone of traditional medicine across diverse cultures worldwide [5, 6]

Ependymal cells, as BBB components, downregulate tight junction proteins (e.g., zonula occludens-1 (ZO-1)) under inflammatory (TNF-) or -syn attack, allowing peripheral pro-inflammatory cytokines (e.g., IL-6), iron/copper ions, and immune cells (e.g., macrophages) to infiltrate the brain parenchyma [272]

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