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A reduction in HbA1c at 12 months compared with baseline was observed among six of the seven patients with data available at both time points (6.1 [5.8, 6.4]% vs
The clinical program involving the triple agonist retatrutide will uniquely be utilizing a basket trial format A basket trial is a type of clinical trial that evaluates the effect of a single drug across multiple disease states that share a common feature, in this case obesity A basket design nests under a single master protocol multiple subtrials, or baskets, each with its own population, endpoints and analysis plan
[6] Slatore CG, Tilles SA
Panels A and B of Figure 1 show the steady state values for the male and female substrates, respectively, and the velocities for CBS, GS, and GPX