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In 2025 the FDA expanded Wegovy's indication to include adults with MASH and moderate to advanced liver fibrosis, on the strength of the ESSENCE Phase 3 trial (FDA Drugs)

Patients without significant cardiovascular disease who prioritize efficacy over regulatory approval status fit the Retatrutide profile well

Any of these warrants staying at the current dose until symptoms resolve before considering the next increase

At this time, it is uncertain how participating beneficiaries will be able to maintain Medicare coverage of their GLP-1 medication for obesity after the Medicare GLP-1 Bridge ends at the end of 2027, pending further action from CMS to implement the BALANCE Model in Medicare Part D in 2028, as described below

To view or add a comment, sign in Whistleblower disclosures to #GPhC surge, highlighting fitness to practise risks - #FitnesstoPractise News by Kings View Medical Defence Whistleblower disclosures to the General Pharmaceutical Council (GPhC) jumped by 208 percent over the past year