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You should avoid Radiesse if: - you have severe allergic reactions that have included throat swelling (anaphylaxis), or have multiple severe allergies, and there is a concern that you might have a reaction to one or more of the ingredients in Radiesse - you have a bleeding disorder - you have an active skin infection near the area you want treated (we will just need to clear up the infection prior to injection) Are there any side effects from Radiesse