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In the seven months since starting the medication, Souza has dropped another 22 pounds and overall, she calls the experience a success

According to NICE guidance, GLP-1 receptor agonists for type 2 diabetes (NG28) are recommended when other treatments have not achieved adequate glycaemic control

It is important that participants in a clinical trial do not stop taking retatrutide without first consulting their trial team , as this may have implications for trial integrity and individual health outcomes

We included all individuals who initiated a combination of metformin and GLP-1 RA or metformin and DPP-4i treatment between January 1 st 2007 and December 31 st 2018