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Ricciuti B, Genova C, and De Giglio A, et al (2019) Impact of immune-related adverse events on survival in patients with advanced non-small cell lung cancer treated with nivolumab: long-term outcomes from a multi-institutional analysis J Cancer Res Clin Oncol 145 (2) 479485 82

TLR pathway activation leads to secretion of pro-inflammatory cytokines, like interleukin (IL)-1, IL-6, and tumor necrosis factor-, as well as type 1 interferon