In addition to directly influencing satiety and appetite control via hypothalamic and hindbrain pathways, GLP-1RAs appear to engage higher-order networks involved in reward processing and emotional regulation, such as the insula, amygdala, and medial prefrontal cortex
This trend aligns with national dispensing patterns, where a study reported a nearly 600% increase in GLP-1 RA prescription fills among adolescents and young adults from 2020 to 2023 ( 9 ) and our own research, which has shown that GLP-1 RAs now make up over 5% of all prescriptions prescribed
Food intake is known to change during the menstrual and/or estrous cycle, with women significantly reducing their food intake in the peri-ovulatory period ( Figure 1 )
The brand's marketing language uses appropriate structure-function framing rather than disease-treatment claims
Diakogiannaki E, Pais R, Tolhurst G, Parker HE, Horscroft J, Rauscher B, et al