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, Comorbidities such as trauma, diabetes mellitus, pregnancy, obesity, hypothyroidism, arthritis, and collagen tissue disorders are often associated with CTS

doi: 10.1016/j.beem.2004.03.003 55 KrassasGEPoppeKGlinoerD

This combination is aimed at patients who are insulin-dependent and need additional glucose control

Once activated, ERK1/2 is transferred to the nucleus, where it phosphorylates transcription factors such as c-Myc and c-Fos, leading to the expression of genes responsible for cellular regulations such as cell proliferation, differentiation, and migration

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