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Nuclear factor erythroid 2 (NFE2)-related factor 2 (NRF-2) was identified as one target of SFN in murine lymphocytes, murine DCs and cancer cells ( Taken together, the existing data create a confusing picture of the effects of SFN on the intracellular redox homeostasis, which might be due to the different systems used, i.e., murine vs

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In addition, the mRNA expression of BMAL1 , PER2 , and CRY1 in visceral fat is closely related to the increase in waist circumference which is an indicator of metabolic syndrome ( The second is that the circadian clock system may control the rate-limiting steps of the metabolic process (Panda et al., 2002)

J Royal Coll Gen Pract 1983