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Theres no strong evidence of harm, but since the data is minimal, most providers advise avoiding semaglutide during breastfeeding

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SCFAs inhibit NF-B activation and promote differentiation of Tregs via histone deacetylase inhibition, enhancing immune tolerance

They found that the predominant impact of SGLT-2 inhibitors is on cardiovascular outcome was driven predominantly by reduction in MACE, total death, HHF, MI, stroke, and CV death