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Final thoughts: GLP-1s need a strategy, not just coverage Covering Wegovy and other GLP-1s can be a high-impact move but only if its done right

Pre-Blend Weekly Schedule Example Pre-blend dose at each titration step Phase Start Weeks 1-4 Draw Volume 0.40 mL (40 units) Reta Delivered 2.0 mg Cag Delivered 0.4 mg Phase Step 1 Weeks 5-8 Draw Volume 0.60 mL (60 units) Reta Delivered 3.0 mg Cag Delivered 0.6 mg Phase Step 2 Weeks 9-16 Draw Volume 0.80 mL (80 units) Reta Delivered 4.0 mg Cag Delivered 0.8 mg Phase Step 3 Weeks 17-20 Draw Volume 1.20 mL (120 units) Reta Delivered 6.0 mg Cag Delivered 1.2 mg Phase Step 4 Weeks 21-24 Draw Volume 1.60 mL (160 units) Reta Delivered 8.0 mg Cag Delivered 1.6 mg Phase Maintenance Weeks 25+ Draw Volume 2.40 mL (240 units) Reta Delivered 12.0 mg Cag Delivered 2.4 mg One injection per week

Photo by Dr Jeff Livingston Long-Term Options for Weight Maintenance Every patients weight journey is unique, and for some, maintenance involves a small, ongoing dose to help keep appetite in check

Med 27 , 10791087 (2021)

At the moment TOI-4127 b is too widely separated from its star for this interaction to happen between the two, but if it's undergoing a momentum exchange with a currently undiscovered second planet in the system, there is still the chance it may become a hot Jupiter