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Previous studies have demonstrated that T4 exerts anti-apoptotic and antioxidant effects by inhibiting ROS production and enhancing cellular survival pathways (42)

60 ,

Lim AS, Kowgier M, Yu L, Buchman AS, Bennett DA

Studies have shown that bitter-tasting pharmaceuticals and substances, including polyphenols such as isosinensetin, bind to bitter taste receptors, and unlike other TAS2R agonists, stimulate GLP-1 secretion in NCI-H716 cells [192] (Fig