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The authors established FOXO4-DRI as a first-in-class senolytic peptide tool for cellular senescence research, with mechanistic selectivity grounded in the elevated FOXO4-p53 interaction in senescent versus non-senescent cells

This work aims to provide a systematic and forward-looking framework to support the industrial and biomedical deployment of copperpeptide therapeutics

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High heterogeneity means studies showed very different results

Summary BPC-157 demonstrates robust regenerative and cytoprotective effects in preclinical studies, positioning it as a potentially valuable tool in musculoskeletal medicine