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Do GLP-1 medications directly cause fatigue

Activation of GLP-1 receptors in the GI tract slow down gastric emptying and slow the transit of food through the intestines

Our findings of glial activation and ependymal lining impairment in cerebral ventricles under STZ exposure align with previously reported increases in GFAP and S100b glial markers in cerebrospinal fluid and blood in this model, indicating blood-brain barrier and blood-CSF barrier dysfunction (Biasibetti et al

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